Amyotrophic Lateral Sclerosis (ALS) News

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Shortcomings in ALS Research: Strategies for Improvement - Neurology Advisor



Neurology Advisor
 
Shortcomings in ALS Research: Strategies for Improvement 
Neurology Advisor
Despite their limited efficacy and survival benefit, riluzole and edaravone remain the only 2 drugs approved by the US Food and Drug Administration for the treatment of amyotrophic lateral sclerosis (ALS). ALS is a progressive neurodegenerative disease ...

 


Antibodies protect nerve-muscle connections in a mouse model of ... - Science Daily



Antibodies protect nerve-muscle connections in a mouse model of ... 
Science Daily
A new study identifies a novel treatment strategy that preserved neuromuscular synapses in a mouse model of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.
Antibodies protect nerve-muscle connections in a mouse model of Lou Gehrig's disease EurekAlert (press release)

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Study finds novel therapeutic strategy that preserves neuromuscular synapses in ALS mouse model - News-Medical.net



News-Medical.net
 
Study finds novel therapeutic strategy that preserves neuromuscular synapses in ALS mouse model 
News-Medical.net
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, causes lethal respiratory paralysis within several years of diagnosis. There are no effective treatments to slow or halt this devastating disease. Mouse models of ALS reproduce ...
Anthony Barraco Makes Donation to ALS Association in Honor of Father EIN News (press release)

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Red Sox, Boston College announce 7th annual ALS Awareness Game to benefit Pete Frates - CLNS Media (blog)



CLNS Media (blog)
 
Red Sox, Boston College announce 7th annual ALS Awareness Game to benefit Pete Frates 
CLNS Media (blog)
Frates was diagnosed with Amyotrophic lateral sclerosis (ALS) at 27 years old. Since then, he, along with his family and friends, have worked tirelessly to raise awareness and funds to find a cure for the disease. In the summer of 2014, Frates ...

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Specific Protein, Sema3A, Affects Survival of Motor Neurons in ALS, Early Research Shows - ALS News Today



ALS News Today
 
Specific Protein, Sema3A, Affects Survival of Motor Neurons in ALS, Early Research Shows 
ALS News Today
One of these factors is semaphorin 3A (Sema3A), a guidance molecule that belongs to a protein family that regulates the growth of the long fibers that extend from neurons, called axons, including those of spinal motor neurons. Motor neuron axons are ...

 


Brain immune system is key to recovery from motor neuron ... - Science Daily



Bioscience Technology
 
Brain immune system is key to recovery from motor neuron ... 
Science Daily
Researchers engineered mice in which the damage caused by a mutant human TDP-43 protein could be reversed by one type of brain immune cell. TDP-43 is a protein that misfolds and accumulates in the motor areas of the brains of ALS patients. They found ...
ALS Mystery Unlocked in Mouse Study - Bioscience Technology Bioscience Technology

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How proteins become dangerous droplets in ALS - Futurity: Research News



Futurity: Research News
 
How proteins become dangerous droplets in ALS 
Futurity: Research News
For the first time, researchers have outlined the atom-by-atom changes in a group of proteins as they form cell-damaging clumps linked to amyotrophic lateral sclerosis (ALS), a group of brain disorders known as frontotemporal dementia, and degenerative ...

 


Takeda looks to oligonucleotides in $230m CNS collaboration - In-PharmaTechnologist.com



In-PharmaTechnologist.com
 
Takeda looks to oligonucleotides in $230m CNS collaboration 
In-PharmaTechnologist.com
... Takeda is currently pursuing for neurological disorders, maximizing our potential for success, and their pipeline and focus are closely aligned with our own,?? Daniel Curran, head of Takeda's Center for External Innovation said. Wave's lead ...
Wave Life Sciences And Takeda Form Global Strategic Collaboration To Advance Therapies For Central Nervous ... Clinical Leader
Takeda and Wave agree $230 million-plus collaboration in CNS disorders The Pharma Letter

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Therapeutic antibodies protected nerve?muscle connections in a ... - Medical Xpress



Medical Xpress
 
Therapeutic antibodies protected nerve?muscle connections in a ... 
Medical Xpress
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, causes lethal respiratory paralysis within several years of diagnosis. There are no effective treatments to slow or halt this devastating disease. Mouse ...
Therapeutic Antibodies Protect Nerve-Muscle Connections in a ... PR Newswire (press release)

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Press Announcements > Statement from FDA Commissioner Scott ... - FDA.gov



Press Announcements > Statement from FDA Commissioner Scott ... 
FDA.gov
New medical breakthroughs are altering how diseases are treated in ways that seemed unimaginable just a decade ago. Perhaps one of the most significant developments is the advent of new gene therapies and drugs that boost the immune system's ability to ...

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