Neoplasm Metastasis News

News of Note?Understanding cancer metastasis; how a superbug secretes toxins; defining breast cancer risk - FierceBiotech



FierceBiotech
 
News of Note?Understanding cancer metastasis; how a superbug secretes toxins; defining breast cancer risk 
FierceBiotech
The team took data from the Cancer Genome Atlas, analyzed which genes were turned on and off in tissues adjacent to the tumors, then used another large cancer database and several smaller ones to identify patterns of inflammation leading to metastasis.

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Pancreatic Neuroendocrine Tumors: State-of-the-Art Diagnosis and Management - Cancer Network



Pancreatic Neuroendocrine Tumors: State-of-the-Art Diagnosis and Management 
Cancer Network
Neuroendocrine tumors (NETs) are widely distributed neoplasms described as epithelial tumors with predominantly neuroendocrine differentiation that share a common phenotype. Regardless of primary site, these tumors have a propensity to metastasize to ...

 


RedHill Biopharma Receives FDA Orphan Drug Designation for MESUPRON for Pancreatic Cancer - GlobeNewswire (press release)



RedHill Biopharma Receives FDA Orphan Drug Designation for MESUPRON for Pancreatic Cancer 
GlobeNewswire (press release)
MESUPRON is a proprietary, first-in-class, orally-administered protease inhibitor, with several potential mechanisms of action to inhibit tumor invasion and metastasis. MESUPRON presents a new, non-cytotoxic approach to cancer therapy. MESUPRON has ...

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Otago scientist out to crack cancer enigma - Otago Daily Times



Otago Daily Times
 
Otago scientist out to crack cancer enigma 
Otago Daily Times
Dr Chatterjee, an expert in epigenetics and molecular biology, will attempt to pinpoint changes in DNA modifications and gene expression patterns between primary tumour cells, tumour cells circulating in the blood and metastatic tumour cells, all from ...

 


Application of multifunctional targeting epirubicin liposomes in the treatment of non-small-cell lung cancer - Dove Medical Press



Application of multifunctional targeting epirubicin liposomes in the treatment of non-small-cell lung cancer 
Dove Medical Press
Abstract: Chemotherapy for aggressive non-small-cell lung cancer (NSCLC) usually results in a poor prognosis due to tumor metastasis, vasculogenic mimicry (VM) channels, limited killing of tumor cells, and severe systemic toxicity. Herein, we developed ...

 


What makes cancer spread? University of Otago study aims to find out - New Zealand Herald



What makes cancer spread? University of Otago study aims to find out 
New Zealand Herald
Using state-of-the-art epigenomic tools, such as single cell level analysis of tumour cells and new epigenetic editing, he will identify drivers of tumour metastasis and specifically engineer these "epigenetic drivers" in the lab to work out how the ...

 


LDHA promotes tumor metastasis by facilitating epithelial?mesenchymal transition in renal cell carcinoma. - UroToday



LDHA promotes tumor metastasis by facilitating epithelial?mesenchymal transition in renal cell carcinoma. 
UroToday
Recently, several reports showed that silencing or inhibition of LDHA could suppress metastasis of human cancer including renal cell carcinoma (RCC). However, the mechanism remains unknown. The role of LDHA in RCC migration and invasion was ...

 


Aprea Therapeutics Announces First Patients Enrolled in Phase Ib/II Clinical Study of APR-246 for the Treatment of ... - Markets Insider



Aprea Therapeutics Announces First Patients Enrolled in Phase Ib/II Clinical Study of APR-246 for the Treatment of ... 
Markets Insider
... and adenocarcinoma, are often diagnosed at an advanced stage when treatment options are limited. Mutations in p53 are found in up to 70% of esophageal cancer patients and are associated with tumor metastasis, poor prognosis and reduced survival.

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Identification and validation of novel prognostic markers in Renal Cell Carcinoma. - UroToday



Identification and validation of novel prognostic markers in Renal Cell Carcinoma. 
UroToday
At present, the surveillance protocols for follow-up of RCC patients after radical nephrectomy are based on the American Joint Committee on Cancers (AJCC) pathological tumor-node-metastasis (TNM) classification system. Other comprehensive staging ...

 


Nearly $4 million in private funds for cancer research - The Jerusalem Post



The Jerusalem Post
 
Nearly $4 million in private funds for cancer research 
The Jerusalem Post
... and tumor blood vessel growth (angiogenesis); cancer stem cells and cellular reprogramming; expression, regulation and mutation of genes; tumor viruses; tumor metastasis; inflammation and cancer; immunology and immunotherapy; protein interactions; ...

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