Prostatic Intraepithelial Neoplasia News

Nerves switch on angiogenic metabolism - Science Magazine



Nerves switch on angiogenic metabolism 
Science Magazine
Indeed, given the requirement for ADR?2 signaling for progression from low-grade prostatic intraepithelial neoplasia (LPIN) to high-grade PIN (HPIN) and the angiogenic switch, perhaps the use of nonselective ?-blockers could prevent progression to ...

 


Atypical small acinar proliferation and two or more cores of high-grade intraepithelial neoplasia on a previous ... - Dove Medical Press



Atypical small acinar proliferation and two or more cores of high-grade intraepithelial neoplasia on a previous ... 
Dove Medical Press
Objective: The objective of this study was to evaluate whether high-grade prostatic intraepithelial neoplasia (HGPIN) and atypical small acinar proliferation (ASAP) predict prostate cancer (PCa) during repeat transperineal template saturation biopsy ...

 


IGF2 imprinting loss promotes cancer - Nature.com



IGF2 imprinting loss promotes cancer 
Nature.com
By crossing this model with an Nkx3.1-mutant mouse model, they were then able to determine whether there was a synergistic effect with Igf2 LOI on development of cancer or prostatic intraepithelial neoplasia (PIN). Biallelic expression occurred in all ...

 


Active surveillance 'reasonable' for younger men with low-risk prostate cancer - Healio



Active surveillance 'reasonable' for younger men with low-risk prostate cancer 
Healio
Of these, 228 (62.6%) showed prostate cancer; 89 (24.5%) appeared benign, 28 (7.7%) had prostatic intraepithelial neoplasia and 10 (5.2%) showed atypia. Researchers reported Kaplan-Meier actuarial freedom-from-treatment rates of 74.3% at 5 years and ...

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Does A High PSA Level Mean I Have Prostate Cancer? - Huffington Post



Huffington Post
 
Does A High PSA Level Mean I Have Prostate Cancer? 
Huffington Post
An elevated PSA number does not always indicate a man has prostate cancer. The PSA test is a blood test used to measure a substance in the blood called prostate specific antigen. It is often the first step in screening for prostate cancer along with ...

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Mechanisms of cancer metabolism: mTORC1 mediates AMD1 - Nature.com



Mechanisms of cancer metabolism: mTORC1 mediates AMD1 
Nature.com
Analysis of metabolic alterations in the prostate at the onset of prostate intraepithelial neoplasia and invasive prostate cancer revealed increases in metabolites related to polyamine synthesis in Pten-null mice and human prostate cancer tissue. Fate ...

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Do This Once A Week To Help Prevent Cancer, Stroke, Heart Disease, and Alzheimers - HuffPost



HuffPost
 
Do This Once A Week To Help Prevent Cancer, Stroke, Heart Disease, and Alzheimers 
HuffPost
I started incorporating fasting about a year ago into my weekly health and fitness program. I had done a number of extended fasts over the years but the logic and practicality always escaped me. You would fast in order to cleanse and detoxify but then ...

 


PCa Active Surveillance Safe, Effective for Younger Patients - Renal and Urology News



Renal and Urology News
 
PCa Active Surveillance Safe, Effective for Younger Patients 
Renal and Urology News
During a median 5 years of follow up, 84.3% of younger patients had repeat prostate biopsy. Two-thirds (62.6%) were found to have PCa, 24.5% benign tumor, 7.7% prostatic intraepithelial neoplasia, and 5.2% atypia. A majority of younger patients ...

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Dr. David Samadi Offers Complimentary Consultation to Men Recently Diagnosed with Prostate Cancer - PR Web (press release)



PR Web (press release)
 
Dr. David Samadi Offers Complimentary Consultation to Men Recently Diagnosed with Prostate Cancer 
PR Web (press release)
Men who undergo a prostate biopsy can receive a parallel diagnosis, high-grade prostatic intraepithelial neoplasia, in which prostate cells are atypical but not yet cancerous. If a biopsy is negative, it doesn't always indicate a man is cancer-free ...

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Active Surveillance for Prostate Cancer: How to Do It Right - Cancer Network



Cancer Network
 
Active Surveillance for Prostate Cancer: How to Do It Right 
Cancer Network
Prostate cancer is the most common malignancy affecting men. There has been a nearly 70% increase in new prostate cancer cases, mostly classified as low risk, that have been diagnosed in early stages as a consequence of prostate-specific antigen (PSA) ...

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